great efforts, we failed to carry our plans through, which made us very disappointed.
A. In place of
B. Instead of
C. In case of
D. In spite of
网友回答
A. In place of
B. Instead of
C. In case of
(答案→)D. In spite of
解析：考查短语辨析。A代替，取代；B而不是；C以防，万一；D尽管。句意：尽管我们作出了巨大努力,我们还是没能完成计划，使得我们非常失望。根据句意说明D正确。