---What do you suppose ______ her look so upset?---______ by her boyfriend again.A.making ; MisunderstoodB.had made ; Being misunderstoodC.made ; Having been misunderstoodD.has made ; Misunderstood
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C解析考查时态及动名词做主语。第一空do you suppose做插入语，后用陈述句语序，根据语意你认为什么使她看起来如此不愉快？应用过去式；第二空回答What，故应回答主语，根据语意再次被他的男朋友误解之后使她看起来如此不愉快，故用现在分词的被动式，所以选C。