His mother is ill. He has to her at home.A. look atB. look afterC. look forD. look into

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解析：此题重点考查动词短语辨析，look at“看”，表动作；look after“照顾、照看”相当于take care of；look for“寻找”表示找的动作；look into“调查”,根据题意，他妈妈生病了，他必须在家照顾他妈妈，故选B