. having hundreds of online friends is great, our real and closest connections still lie with those who are a part of our daily lives.
A. As
B. Once
C. While
D. When
网友回答
A. As
B. Once
(答案→)C. While
D. When
解析：考查连接词的用法。句意“尽管有成百上千的网友很不错，但是，我们真实的、最亲密的联系还是和日常生活中的朋友。”A“由于，当”；B“曾经，一旦”；C“尽管”；D“当，既然”。While在此表示让步。故选C。