Steve has to get up at 5:00 A.M. to get to school. this , he has never missed a class.
A. In contrast to B. Apart from C. In addition to D. In spite of
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解析：句意，Steve不得不早晨五点钟起床去上学。尽管如此，他从来没有错过一节课。In contrast to相比之下Apart from除此之外In addition to除……之外In spite of尽管，根据题意，故选D。