Though he failed many times in election, he never lost heart and at last he was elected President of the USA.
A. the ; a B. a ; the C. his; the D. / ; /
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解析：第一空考查固定短语中的冠词，lose heart意为：申请信心。不用冠词；第二空表示头衔的名词，作宾补，其前不用冠词。句意：虽然他在竞选中失败多次，他从未失去信心。最后他被选为美国总统。故选D。