So by the 1600’s Shakespeare was able to a wider vocabulary than ever before.
A. take use of
B. make use on
C. take use up
D. make use of
网友回答
A. take use of
B. make use on
C. take use up
(答案→)D. make use of
解析：考查固定词组。Make use of/take advantage of利用；句意：所以到了1600年的时候，莎士比亚已经可以使用比以前多得多的词汇了。故D正确。