Tony can’t have received the invitation. , he would have attended your birthday party yest

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A. Therefore
(答案→)B. Otherwise
C. However
D. Besides
解析：此题易误选A。therefore意为“因此，所以”；otherwise意为“否则”；however意为“然而”；besides意为“况且”。根据句意“托尼不可能收到你的邀请，否则的话，题在昨天就会参加你的生日聚会了”可知，答案为B。