＿＿＿＿＿ heat is different from temperature?
A. How do you think
B. How you think
C. What do you think
D. What you think
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(答案→)A. How do you think
B. How you think
C. What do you think
D. What you think
解析：do you think为插入语置于疑问词之后，而特殊疑问句本身的主语、谓语用陈述语序。