his financial problems , his wife also left him , which made him very depressed .
A. In case of
B. Except
C. On top of
D. On account of
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A. In case of
B. Except
(答案→)C. On top of
D. On account of
解析：词义辨析题。A. In case of 万一 B. Except 除…之外 （不包括在内） C. On top of 除…之外（还） D. On account of 由于 除了财政问题他的妻子也离开了他，这使得他非常低落。 根据句意选C