While intelligent people can often the complex, a fool is more likely to complicate the

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A. sacrifice
B. substitute
(答案→)C. simplify
D. survive
解析：C　考查动词辨析。句意：聪明人常常能使复杂的事简单化，然而愚蠢的人更有可能使简单的事复杂化。sacrifice牺牲，奉献；substitute代替，取代；simplify使……简单化；survive幸存，幸免于。前后分句表对比，故C项符合句意。