Mr. Smith wanted to buy the house and he told me that the house cost，it would be worth it.

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A. however
B. how much
(答案→)C. whatever
D. what
解析：考查让步状语从句。Whatever引导让步状语从句，并作为cost的宾语。A不能做宾语，B不能引导让步状语从句。结合句意可知C正确。句意：斯密斯先生想要买那栋房子，他告诉我无论房子值多少钱，都是值得的。