Little at that time that this“boring”subject would become his favourite later on.A. he k

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A. he knew
B. he has known
(答案→)C. did he know
D. has he known
解析：句意：在那时他几乎不知道这样枯燥的课程会成为他后来最喜欢的。Little“几乎没有”是否定词，放在句首，这句话用部分倒装，be动词/情态动词/助动词放在主语前面。因为是at that time那时发生的事情，用一般过去式，所以选C。