Generally speaking, clothes made of man-made materials is less fortable than made of natural fibers like cotton, wool or silk.
A. that
B. it
C. those
D. One
网友回答
A. that
B. it
(答案→)C. those
D. One
解析：考查代词。That特指不可数名词单数或者不可数名词 it特指上文提到的同一个事物 those特指可数名词复数 one泛指可数名词单数，此处those代指的是clothes,可数名词特指
句意为，一般来说，由人造材料制成的衣服没有自然纤维，例如棉花，羊毛或者丝，制成的衣服穿起来舒服。