Cheer up! Everyone may have periods in their lives everything seems tough.
A. when
B. where
C. which
D. that
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(答案→)A. when
B. where
C. which
D. that
解析:考查定语从句。定语从句When everything seems tough修饰先行词periods, 本定语从句很完整,且先行词表示时间,所以使用关系副词when.句意:振作起来!在人生中每个人都有什么都不顺利的时期的。