John invited approximately 40 guests to his wedding, most of are family members.
A. whom
B. that
C. them
D. which
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(答案→)A. whom
B. that
C. them
D. which
解析：句意：约翰大约邀请了40个客人到他的婚礼上，其中大部分都是家庭成员。这是用了定语从句，用关系代词，不能用them，先行词是guests，排除D，定语从句用了most of后面接宾格whom引导定语从句，that不能和介词连用。选A。