It is difficult work nobody can do it wellA. such; thatB. such a; thatC. so; thatD. so

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A. such; that
(答案→)B. such a; that
C. so; that
D. so a; tha
解析：such……that和so……that都表示如此……以至于，区别就是such是形容词，修饰名词，意思是如此的这样的；so是副词，修饰动词，意思是如此这样。句意：这是如此困难的一项工作，以至于没有人能做好。difficult work中心词是work，故选B。