Some children want to challenge themselves by learning a language different from their p

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(答案→)A. what
B. that
C. which
D. one
解析：考查宾语从句。本题中的what引导的是一个宾语从句what their parents speak at home作为介词from的宾语，what在句中作为动词speak的宾语。句意：一些孩子想要挑战自己去学一种与父母在家里所讲的不一样的语言。One不能引导宾语从句，that不能在宾语从句中做成分；which是指特定范围之内的某一个。故A正确。