As long as you are confident and determined, you will whatever difficulties you face.
A. overe
B. confirm
C. grasp
D. acquire
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(答案→)A. overe
B. confirm
C. grasp
D. acquire
解析：A. Overe克服，B. Confirm证实，C. Grasp掌握，D. Acquire获得，句意：只要你很自信和有决心，你就会克服遇到的任何困难。所以选A。