Don’t annoy me again. I must warn you that my patience is almost .
A. in charge
B. in ruins
C. at present
D. at an end
网友回答
A. in charge
B. in ruins
C. at present
(答案→)D. at an end
解析：句意：不要再打搅我了。我必须警告你我的耐心几乎用尽了。in charge主管；in ruins严重受损；at present目前；at an end耗尽，选D。