I was deeply impressed the speech by the mayor of Shanghai before the final voting for E

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A. to
B. on
C. over
(答案→)D. with
解析：固定搭配be impressed with…对…留下深刻印象;句义：我对上海市长在2010年世博会最终投票前的发言留下了深刻的印象。故D正确。动词impress还可以构成固定搭配impress sb with sth以…给某人留下深刻印象。本句是起被动语态转换的形容词短语。故D正确。