You had better book rooms at the hotel in advanceyou should find no room on your arrival.

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A. so that
B. even if
C. in case
D. now that
解析：选C。考查状语从句。句意: 你最好提前在旅馆订房间, 以防你到达时找不到房间了。in case意为“以防; 免得”, 引导目的状语从句。
【变式训练】
(2013·烟台模拟)We’d better stay here a little longer    he turns up unexpectedly.
A. although     B. in case          C. since       D. if only
选B。考查状语从句。句意: 我们最好在这里多待一会儿, 免得他突然出现。此处in case引导一个目的状语从句。
【知识拓展】in case作为短语连词的用法
in case作短语连词, 能引导状语从句。
就其词义和语法职能来分, 可引导两种从句。
其一: in case/just in case引导目的状语从句作“以免, 以备, 以防”等解。例如:
He takes a torch in case it gets dark before he returns.
他带了手电筒, 以备天黑以后回家之用。
Please remind me of it again tomorrow in case I forget.
请你明天再提醒我一下, 免得我忘记。
其二: in case接条件状语从句, 意为“如果, 万一”。例如:
In case we fail, we won’t lose heart.
万一我们失败, 我们决不会失去信心。
Take a hat with you in case the sun is very hot.
倘若太阳很厉害, 你就把帽子戴上。
In case he arrives before I get back, please ask him to wait.
万一我回来前他先到了, 请让他等我。
注意: in case引出的条件状语从句所表示的意义是“预防某种情况的出现”; 如果从句说的是一般的假设或条件, 则要用if。请比较:
I’ll tell him about the matter if I meet him. 　(不用in case)
Take an umbrella in case it rains. 　(不用if)
在上下文意义很明确时, 有时可省去in case后从句的内容。例如:
I don’t think it will rain, but I’ll take an umbrella in case(it rains).