Is it the years _______ you worked in Africa as a doctor _______ have a great effect on your literary works?
A.that; where
B.that; that
C.when; where
D.when; that
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D解析该题既做到了把定语从句放到疑问句中，又做到了把定语从句放到强调结构里进行考查。第一个空是个定语从句，先行词是the year，when在定语从句里是时间状语；第二个空是it is …that…强调结构。