基因芯片中UPD是什么意思 英语
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【答案】 UPD 是uniparental disomy的缩写:
Uniparental disomy (UPD) occurs when a person receives two copies of a chromosome,or of part of a chromosome,from one parent and no copies from the other parent.UPD can be the result of heterodisomy,in which a pair of non-identical chromosomes are inherited from one parent (an earlier stage meiosis I error) or isodisomy,in which a single chromosome from one parent is duplicated (a later stage meiosis II error).Because it may lead to the duplication of lethal recessive genes,isodisomy is potentially dangerous,while heterodisomy is essentially benign.