The number of people this happens is not very large.A. with whomB. to whichC. to whomD. o

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A. with whom
B. to which
(答案→)C. to whom
D. on which
解析：考查定语从句，先行词是people，定语从句中happen后面缺少介词to，所以是to whom引导定语从句，句意：发生这件事的人的数量不多。选C。