It took him a long time to the skills needed to bee a professional artist.
A. acquire
B. inquire
C. Require
D. request
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(答案→)A. acquire
B. inquire
C. Require
D. request
解析：考查动词。acquire“得到；获得”，符合句意。inquire“询问”； require“需要”； request“请求”。 句意：他花了很长一段时间才学会成为一名专业艺术家所需要的技能。故A正确。