I really don’t know about it.A. what to doB. how to doC. to do whatD. how can I do

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(答案→)A. what to do
B. how to do
C. to do what
D. how can I do
解析：A 考查疑问词加不定式。do是及物动词，必须有自己的宾语。选B的话，do缺少宾语，故选A，what作do的宾语。What to do = how to do it。